Pro League
1st leg 23/04/22 20:45
KV Mechelen 
RC Sporting Charleroi24/04/22 13:30
Club Brugge KV 
Royal Antwerp FC24/04/22 16:00
KAA Gent 
KRC Genk24/04/22 18:30
Royale Union Saint-Gilloise 
RSC Anderlecht29/04/22 20:45
KRC Genk
KV Mechelen30/04/22 18:30
RC Sporting Charleroi
KAA Gent01/05/22 13:30
Royal Antwerp FC
Royale Union Saint-Gilloise01/05/22 18:30
RSC Anderlecht
Club Brugge KV1st leg 06/05/22 20:45
RC Sporting Charleroi
KRC Genk1st leg 07/05/22 20:45
KAA Gent
KV Mechelen1st leg 08/05/22 13:30
Royale Union Saint-Gilloise
Club Brugge KV08/05/22 18:30
Royal Antwerp FC
RSC Anderlecht2nd leg 10/05/22 18:45
KV Mechelen
KAA GentGlobal 1–3
2nd leg 10/05/22 21:00
KRC Genk
RC Sporting CharleroiGlobal 5–4
2nd leg 11/05/22 20:30
Club Brugge KV
Royale Union Saint-GilloiseGlobal 3–0
2nd leg 14/05/22 20:45
RC Sporting Charleroi
KV MechelenGlobal 3–3
Pro League 21/22, Championship Round — 21/22
| # | Team | Pts | P | W | D | L | GF | GA | GD | Form |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 50 | 6 | 4 | 2 | 0 | 8 | 2 | 6 |  | |
| 2 | 46 | 6 | 2 | 1 | 3 | 5 | 5 | 0 |   | |
| 3 | 40 | 6 | 2 | 2 | 2 | 8 | 7 | 1 |  | |
| 4 | 36 | 6 | 1 | 1 | 4 | 3 | 10 | -7 |   |
- Champions League
- Conference League Qualification
- Qualification Playoffs
Top players
Scorers
- 1Deniz Undav26 Royale Union Saint-Gilloise
- 2Michael Frey24 Royal Antwerp FC
- 3Tarik Tissoudali21 KAA Gent
- 4Paul Onuachu21 KRC Genk
- 5Jelle Vossen17
SV Zulte Waregem - 6Joshua Zirkzee16 RSC Anderlecht
- 7Nikola Storm15 KV Mechelen
- 8Charles De Ketelaere14 Club Brugge KV
- 9Dante Vanzeir14 Royale Union Saint-Gilloise
- 10Shamar Nicholson13 RC Sporting Charleroi
Assists
- 1Junya Ito16 KRC Genk
- 2Xavier Mercier14 Oud-Heverlee Leuven
- 3Deniz Undav12 Royale Union Saint-Gilloise
- 4Ryota Morioka12 RC Sporting Charleroi
- 5Noa Lang12 Club Brugge KV
- 6Jean-Luc Dompé12 SV Zulte Waregem
- 7Sergio Gómez11 RSC Anderlecht
- 8Dino Hotić10 Cercle Brugge
- 9Hugo Cuypers10 KV Mechelen
- 10Dante Vanzeir10 Royale Union Saint-Gilloise