CONMEBOL Sudamericana
1st leg 25/10/17 02:45
Libertad 
Racing Club1st leg 25/10/17 00:15
Nacional Asunción 
CA Independiente1st leg 25/10/17 01:45
Fluminense 
Flamengo1st leg 26/10/17 01:45
Sport Recife 
Junior Barranquilla2nd leg 01/11/17 23:15
Racing Club
LibertadGlobal 0–1
2nd leg 01/11/17 00:45
Flamengo
FluminenseGlobal 4–3
2nd leg 02/11/17 23:15
CA Independiente
Nacional AsunciónGlobal 6–1
2nd leg 03/11/17 01:45
Junior Barranquilla
Sport RecifeGlobal 2–0
Top players
Scorers
- 1Luis Miguel Rodríguez5
Atlético Tucumán - 2Jhon Cifuente5
Universidad Católica del Ecuador - 3Felipe Vizeu5 Flamengo
- 4Leandro Fernández4 CA Independiente
- 5Maximiliano Freitas4
Oriente Petrolero - 6Óscar Cardozo4 Libertad
- 7Henrique Dourado4 Fluminense
- 8André Balada4 Sport Recife
- 9Emanuel Gigliotti4 CA Independiente
- 10Santiago Salcedo4 Libertad